Evidence |
Classic macrophage marker genes (CD14, CD163 and FCGR3A) were highly expressed in IR-MΦ, I-MΦ and iFIB.R-MΦ diferentially expressed genes for signaling pathways related to immune regulation such as Stabilin 1(STAB1), a homeostatic receptor linking signals from extracellular to intracellular vesicular processes23, Tioredoxin Interacting Protein (TXNIP), an inhibitor of NF-κB activity24 and CD169, a macrophage specifc markerof immunoregulation and infammation25 (Fig. 2d and supplementary Fig. S2). |