| Evidence |
our results identified monocyte (Cd14, Fcgr3), macrophage (Adgre1, Csf1r), dendritic cell (Flt3), T cell (Cd3g, Cd4, Cd8b1) and natural killer cell (Ncr1), B cell (Cd19, Cd79a, Jchain) and plasma cell (Jchain, Sdc1), Endothelial cells (Pecam1, Cdh5), and mesenchymal stromal/stem cell (MSC, expressing Lum, Dcn, Cd34, Pdgfra) (Online Figure III).Cluster 3 and 4 corresponded to ECs, with expression of endothelial-specific gene (Pecam1, Cdh5, Kdr, Tie1; Figure 5C);we detected Aqp1 as a possible specific marker for cluster 3, and Lyve1, a lymphatic endothelial marker35, for cluster 4 (Figure 5D). Cluster 4 was then annotated as lymphatic Endothelial cellss (LEC), while cluster 3 annotated as AQP1+ ECs |
