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ID 8741
Class Mammalia
Species Mouse
Tissue Spinal cord
Sample Tissue
Disease type Experimental autoimmune encephalomyelitis
Cell type Microglia cells
Cell type (subtype) Microglia cells
Cell marker Cx3cr1, Tmem119, P2ry12
Frequency
PubMed ID 32149735
Journal J Clin Invest
SCI IF 12.282
Evidence Hierarchical clustering of the cells identified 5 main clusters of immune cells (Figure 3A), which expressed canonical markers of microglia (Tmem119, _2ry12, and_x3cr1), macrophages (Cd14, _yz2, _y6c2, and_d68), Th cells (Cd3d, _d3e, _d3g, and_d4), granulocytes (Retnlg, _100a8, and_100a9), and dendritic cells (Kmo, _lt3, _cr7, and_cl17) (Figure 3A)
Title Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS
Authors Zhilin Li et al.
Date 2020.4
Data available GSE129105