Search | Result
| ID | 8795 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Spleen |
| Sample | Tissue |
| Disease type | Acute and chronic LCMV infections |
| Cell type | CD8 T cells |
| Cell type (subtype) | Memory precursor cells |
| Cell marker | Ccr7, Sell, Id3, Tcf7, Bcl2 |
| Frequency | |
| PubMed ID | 31209400 |
| Journal | Nat Immunol |
| SCI IF | 20.479 |
| Evidence | Cells in this cluster exhibited elevated expression of type I and type II interferon gene signatures and a transcriptional signature of memory precursor cells, including upregulation of Bcl2, Ccr7, Id3, Sell and Tcf7, and downregulation of Ccr2, Gzmb, Id2, Klrg1 and Zeb2 |
| Title | Single-cell RNA-seq reveals TOX as a key regulator of CD8 + T cell persistence in chronic infection |
| Authors | Chen Yao et al. |
| Date | 2019.7 |
| Data available | GSE119943 |
