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ID 8684
Class Mammalia
Species Mouse
Tissue Small intestine
Sample Tissue
Disease type Normal
Cell type Enteroendocrine cells
Cell type (subtype) Enteroendocrine cells
Cell marker Chga, Chgb, Gip, Cck, Sct, Ghrl, Glp1, Pyy, Nts
Frequency
PubMed ID 28686870
Journal Cell Stem Cell
SCI IF 20.86
Evidence In agreement with bulk RNA-seq data, >92% of individual Bmi1-GFP+ cells expressed EE secretory marker mRNAs such as Chga, Chgb, Cck, Sct, Gip, Glp-1, Pyy, and Nts, indicating predominant identity as EE lineage cells EE cells (Clusters 3, 6, 7, 10, and 12) were annotated based on the enrichment of markers such as Chga and Chgb.
Title Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity
Authors Kelley S. Yan et al.
Date 2017.7
Data available GSE99457