Search | Result
| ID | 8668 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Small intestine |
| Sample | Tissue |
| Disease type | Normal |
| Cell type | Label-retaining cells (lrcs) |
| Cell type (subtype) | Label-retaining cells (lrcs) |
| Cell marker | Lgr5, Ascl2, NFAT5, NFATc3 |
| Frequency | |
| PubMed ID | 28686870 |
| Journal | Cell Stem Cell |
| SCI IF | 20.86 |
| Evidence | The tuft/EE co-expressing population exhibited detectable expression of Lgr5 and Ascl2, but not Olfm4 or other canonical CBC signature genes. Furthermore, these cells also exhibited Nfat5 and Nfatc3 (Figure 4B), potentially consistent with the previously described LRC, a secretory progenitor that co-expresses stem cell and secretory lineage markers including EE loci (Buczacki et al., 2013). |
| Title | Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity |
| Authors | Kelley S. Yan et al. |
| Date | 2017.7 |
| Data available | GSE99457 |
