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ID 855
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Blood
Disease type Dengue virus (DENV) and other viral diseases
Cell type CD8 T cells
Cell type (subtype) Memory CD8 T cells
Cell marker CD69, CD25
Frequency
PubMed ID 31413301
Journal Nat Commun
SCI IF 12.121
Evidence DENV-reactive memory CD8+_ cells (day 120) were identified by their upregulation of the early activation markers CD25 and CD69. In addition, vaccine-reactive CD8+ T cells from an early post-vaccination time point (day 14) were identified by expression of the activation markers CD38 and HLA-DR and isolated by flow sorting.
Title Dissecting the heterogeneity of DENV vaccine-elicited cellular immunity using single-cell RNA sequencing and metabolic profiling
Authors Adam T Waickman et al.
Date 2019.8
Data available GSE132950