Search | Result
| ID | 8444 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Retina |
| Sample | Organoids |
| Disease type | Spontaneous uveoretinitis |
| Cell type | T cells |
| Cell type (subtype) | Regulatory T cells (Treg) |
| Cell marker | Cd4, Foxp3, Il10 |
| Frequency | |
| PubMed ID | 31843893 |
| Journal | Proc Natl Acad Sci U S A |
| SCI IF | 9.412 |
| Evidence | By classifying cells according to known markers (Fig. 2B and SI Appendix, Table S2), we identified the following 6 classes: Th1 cells (T-bet+, Ifng+, Cxcr6+, Cd4+, Cd8a_, Klra1_), Cd8a+ T cells (Cd8a+, Cd4-, Klra1_), T follicular helper (Tfh) cells (Bcl6+, Cxcr5+, Cd4+, Cd8a_), regulatory T (Treg) cells (Foxp3+, Cd4+, Il10+), NK cells (Klra1+, Cd3e_, Cd4_, Cd8a_), and NK T cells (Klra1+, Cd3e+, Cd8a+). |
| Title | Comprehensive analysis of a Mouse model of spontaneous uveoretinitis using single-cell RNA sequencing |
| Authors | Jacob S Heng et al. |
| Date | 2019.12 |
| Data available | GSE132229, GSM3854512_3854519 |
