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ID 8389
Class Mammalia
Species Mouse
Tissue Retina
Sample Organoids
Disease type Spontaneous uveoretinitis
Cell type Macrophages
Cell type (subtype) Monocyte-derived macrophages
Cell marker Trem2, Fabp4, Mmp12, Hexb, Atp6v0d2, F7, Pla2g2d, Mmp13, Tmem26
Frequency
PubMed ID 31843893
Journal Proc Natl Acad Sci U S A
SCI IF 9.412
Evidence Fig. S3A. Our pseudotime analysis expands on this dynamic picture by implying that many monocytes transition from a state characterized by markers such as Ccr2 and Ly6c2 to a mo-MΦ state characterized by markers such as Hexb and Trem2
Title Comprehensive analysis of a Mouse model of spontaneous uveoretinitis using single-cell RNA sequencing
Authors Jacob S Heng et al.
Date 2019.12
Data available GSE132229, GSM3854512_3854519