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ID 7846
Class Mammalia
Species Mouse
Tissue NA
Sample Tissue
Disease type obesity
Cell type Tam, m1-like
Cell type (subtype) Tam, m1-like
Cell marker Itgam, Adgre1, C1qc, Sepp1, Cxcl9, Cxcl10, Ccl2, Ccl12
Frequency
PubMed ID 33301708
Journal cell
SCI IF 38.637
Evidence Mesenchymal cells were identified by lack of endothelial (Pecam1, encoding for CD31) and hematopoietic (Ptprc, encoding for CD45) cell markers, and by expression of mesenchymal genes uch as Thy1 and Fap. Expression of Pdpn was used to further distinguish between CAFs (Fap+Pdpn+) and cancer-associated pericytes (CAPs, Fap+Pdpn-), as previously described
Title Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
Authors Alison E Ringel et al.
Date 2020.12
Data available GSE160687