ID |
8071 |
Class |
Mammalia |
Species |
Mouse |
Tissue |
Pancreas |
Sample |
Tissue |
Disease type |
Pancreatic ductal adenocarcinoma |
Cell type |
Fibroblasts |
Cell type (subtype) |
Cancer associated fibroblasts (CAFS) |
Cell marker |
Cxcl1, PDGFR, PDPN, Il1a, Il6, Lif, Csf3 |
Frequency |
|
PubMed ID |
30366930
|
Journal |
Cancer Discov |
SCI IF |
29.497 |
Evidence |
we thus determined the effects of NF-κB pathway inhibition on the expression of iCAF markers, such as Il1a, Il6, Lif, Cxcl1 and Csf3 |
Title |
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFbeta to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma |
Authors |
Giulia Biffi et al. |
Date |
2019.2 |
Data available |
GSE114417 |