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ID 5893
Class Mammalia
Species Mouse
Tissue Embryos
Sample Tissue
Disease type Normal
Cell type Pluripotency cells
Cell type (subtype) Pluripotent epiblast (epi)
Cell marker Nanog, Sox2, Nodal
Frequency
PubMed ID 30959515
Journal Nature
SCI IF 49.962
Evidence Gene_xpression plots of AVE (Cer1 and Dkk1), visceral_ndoderm (Eomes, Foxa1 and Ttr), and_isceral_ndoderm and EPI (Nodal) markers along EPI, and PrE and visceral_ndoderm lineages from E3.5_E5.5.SOX2 and GATA6 were used as EPI and PrE lineage markers, respectively;ICM cell-fate specification is driven, in part, by the lineage-specific transcription factors GATA6 and NANOG, which are co-expressed in uncommitted ICM and exclusively expressed in—and required for—PrE and EPI, respectively
Title The emergent landscape of the Mouse gut endoderm at single-cell resolution
Authors Sonja Nowotschin et al.
Date 2019.5
Data available GSE123046