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ID 6589
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type NA
Cell type Fibroblasts
Cell type (subtype) Fibroblasts
Cell marker NA
Frequency
PubMed ID 31723062
Journal JCI Insight
SCI IF 6.205
Evidence Using t-distributed stochastic neighbor embedding (tSNE) (10), global dimension reduction was constructed from all samples to visualize clusters that were defined by cell-specific gene markers (Figure 1A and Supplemental Table 2). / To identify specific markers for each cluster and consequently annotate them with the respective heart cell type, we applied Seurat “FindAllMarkers� function using the AUCbased scoring classifier with default parameters. We used the default Wilcoxon’s rank-sum test for the specific cell type analysis.
Title Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart
Authors Ramon Vidal et al.
Date 2019.11
Data available NA