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ID 2773
Class Mammalia
Species Homo sapiens
Tissue Kidney
Sample Organoids
Disease type Autosomal recessive polycystic kidney disease
Cell type Endothelial cells
Cell type (subtype) Vascular endothelial cells
Cell marker CDH5, FLT1, KDR, CD34, CD31, TAL1, FLI1, MEF2C
Frequency
PubMed ID 31303547
Journal Cell Stem Cell
SCI IF 20.86
Evidence Immunofluorescence analysis of nephron progenitor markers (SIX1, SIX2, SALL1) andvascular endothelial markers (KDR, CD31) in day 11 differentiating cells.Violin plots and t-SNE plots of genes involved in vascularization based on expression of ligands(VEGFA) in maturing podocytes (OLFM3) and receptors in vascular Endothelial cellss (KDR, FLT1), respectively.Figure S2E
Title Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
Authors Jian Hui Low et al.
Date 2019.9
Data available GSE132026