ID |
2773 |
Class |
Mammalia |
Species |
Homo sapiens |
Tissue |
Kidney |
Sample |
Organoids |
Disease type |
Autosomal recessive polycystic kidney disease |
Cell type |
Endothelial cells |
Cell type (subtype) |
Vascular endothelial cells |
Cell marker |
CDH5, FLT1, KDR, CD34, CD31, TAL1, FLI1, MEF2C |
Frequency |
|
PubMed ID |
31303547
|
Journal |
Cell Stem Cell |
SCI IF |
20.86 |
Evidence |
Immunofluorescence analysis of nephron progenitor markers (SIX1, SIX2, SALL1) andvascular endothelial markers (KDR, CD31) in day 11 differentiating cells.Violin plots and t-SNE plots of genes involved in vascularization based on expression of ligands(VEGFA) in maturing podocytes (OLFM3) and receptors in vascular Endothelial cellss (KDR, FLT1), respectively.Figure S2E |
Title |
Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network |
Authors |
Jian Hui Low et al. |
Date |
2019.9 |
Data available |
GSE132026 |