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ID 5784
Class Mammalia
Species Mouse
Tissue Digit tip
Sample Tissue
Disease type Digit tip regeneration
Cell type Epithelial cells
Cell type (subtype) Epithelial cells
Cell marker Krt14, Krt5, Krt10
Frequency
PubMed ID 31902657
Journal Dev Cell
SCI IF 10.092
Evidence Clusters or cell types were identified based on the expression of the following marker genes (amongst others) as Schwann lineagecells -Sox10(SRY-box transcription factor 10), Sox2(SRY box transcription factor 2) andPlp1(Proteolipid protein 1); Endothelial cellss-Pecam1(Platelet and Endothelial cells adhesion molecule 1), Tie1(Tyrosine kinase with immunoglobulin like and EGF like domains 1)andCdh5(Cadherin 5); vascular smooth muscle/pericytes -Myh11(Myosin heavy chain 11), Rgs5(Regulator of G protein signalling5), Mylk(Myosin light chain kinase) andPdgfrb(Platelet derived growth factor receptor beta); mesenchymal cells
Title Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration
Authors Mekayla A Storer et al.
Date 2020.2
Data available GSE135985