| Evidence |
Clusters 0 and 4 are enriched in macrophage-related markers, including Cd68, Csf1r, Cd14 and Mafb (Figure 2D and Figure 2—figure supplement 1B). Clusters 1 and 2 are enriched in genes associated with T cells (Cd3d, Cd8b1) and B cells (Igkc, Ms4a1). Clusters 3 and 7 express genes associated with dendritic cells including Ccl22 and Xcr1, respectively. Cells associated with cluster 5 express NK-cell-related genes (Ncr1, Nkg7). Cluster 6 represents a proliferative population with the expression of genes such as Mki67 and Stmn1. Cells in cluster 8 are associated with the expression of the monocyte marker Ly6c2. Finally, Cluster 9 appears to represent a small population of contaminating epithelial cells (Prlr, Krt18). |
