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ID 6198
Class Mammalia
Species Mouse
Tissue Gastruloids
Sample Tissue
Disease type Normal
Cell type Somite
Cell type (subtype) Somite
Cell marker Aldh1a2, Uncx4.1
Frequency
PubMed ID 32076263
Journal Nature
SCI IF 49.962
Evidence Olfr129_nd_necut1, head mesenchyme (cluster9);_tv2, haemato-endothelial progenitors (bottom part of cluster10);_dr, haemato-endothelial progenitors and endothelium (cluster10);_dh5_nd_ie1, endothelium (top part of cluster10);_bx4, _oxa11, _ss1_nd_mp7, allantois (cluster11);_phx2, _t1, _tf1_nd_ou5f1, primordial-germ-cell-like or extra-embryonic ectoderm (cluster12);_ol4a1, _pcam_nd_ox17, endoderm (cluster13)._, Mean log normalized expression of relevant markers of clusters 1_8 plotted on the UMAP plot from Fig.1a._and2_nd_ata6, heart (cluster1);_eox2_nd_ax3, differentiated somite (cluster3);_ldh1a2_nd_ncx4.1, somite (cluster4);_fng, _esp2, _ipply2_nd_ll1, differentiation front (cluster5);_es7_nd_bx6, presomitic mesoderm (cluster 6);_nt3a, _gf17, _gf8, _yp26a1, _kx1-2_nd_, tail bud containing neuromesodermal progenitors (cluster7);_ax6, _ox1, _es3_nd_ox2, differentiated neural cells (spinal cord; cluster8).
Title Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids
Authors Susanne C. van den Brink et al.
Date 2020.2
Data available GSE123187