Search | Result
| ID | 542 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Blood |
| Sample | Blood |
| Disease type | COVID-19 |
| Cell type | Macrophages |
| Cell type (subtype) | Alveolar macrophages |
| Cell marker | APOE, MARCO, MSR1, FBP1 |
| Frequency | |
| PubMed ID | 32810439 |
| Journal | Cell |
| SCI IF | 38.637 |
| Evidence | we identified 5 regions based on DEGsacross pooled data from all samples (Figures 7F and S7I), including T cells (characterized by expression the NKG7, CD8A, CST7, GZMB, and GZMA genes), B cells (IGLV3-19, IGHV4-34, IGHG1, IGHA1, and JCHAIN), neutrophils (G0S2, RSAD2, IL1R2, and IL1RN), alveolar macrophages (APOE, MSR1, MARCO, and FBP1), and monocytes/macrophages(FN1, CXCL10, CD68, and NUPR1). |
| Title | Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19 |
| Authors | Aymeric Silvin et al. |
| Date | 2020.9 |
| Data available | GSE145926 |
