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ID 538
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Blood
Disease type COVID-19
Cell type Monocytes
Cell type (subtype) Classical monocytes
Cell marker CD14, ITGAM, KLF4
Frequency
PubMed ID 32810439
Journal Cell
SCI IF 38.637
Evidence Cellsof cluster 1 expressed CD14, ITGAM (encoding CD11b), andKLF4 while poorly expressing FCGR3A (encoding CD16), suggesting classical monocytes. Cells of cluster 3, which expressed high levels of FCGR3A and low levels of CD14, maycorrespond to non-classical monocytes, and cluster 2, in whichcells expressed CD14 and FCGR3A, evoked intermediatemonocytes (Figure 3A)
Title Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19
Authors Aymeric Silvin et al.
Date 2020.9
Data available GSE145926