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ID 5125
Class Mammalia
Species Mouse
Tissue Brain
Sample Tissue
Disease type Chronic autoimmune neuritis
Cell type Schwann cells
Cell type (subtype) NmSCs
Cell marker Erbb3, S100b, Ngfr, p75
Frequency
PubMed ID 32295886
Journal Proc Natl Acad Sci U S A
SCI IF 9.412
Evidence One cluster expressed pan-Schwann cellmarkers (e.g., Erbb3 and s100b), One cluster expressed pan-Schwann cell markers (e.g., Erbb3 and s100b) and also coexpressed myelin protein genes (e.g., Mbp and Plp1), while another cluster did not express myelin protein genes, but a known SC receptor (Ngfr/p75) (Fig. 1C and SI Appendix, Table S3). We named these clusters myscs and nmscs, respectively (Fig. 1A).
Title Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity.
Authors Wolbert J et al.
Date 2020.4
Data available GSE142541