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ID 489
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Cell line
Disease type Normal
Cell type Haematopoietic cells
Cell type (subtype) Haematopoietic cells
Cell marker RUNX1, SPI1
Frequency
PubMed ID 31907413
Journal Nat Cell Biol
SCI IF 14.612
Evidence Based on marker genes representative of specific cell clusters derived from the above analyses, four groups of cells including endothelial (CAV1+CLDN5+), haematopoietic (SPI1+ orRUNX1+GATA3_CAV1_), T-lineage (GATA3+CD3E+KLRB1_)and NKT-lineage (GATA3+KLRB1+) progenitors were selectedfor single-cell trajectory analysis using the Monocole algorithm
Title Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in Human pluripotent stem cell-derived haematopoietic organoids
Authors Ali Motazedian et al.
Date 2020.1
Data available GSE124172