Search | Result
ID | 4857 |
---|---|
Class | Mammalia |
Species | Mouse |
Tissue | Blood |
Sample | Blood |
Disease type | NA |
Cell type | Erythrocytes |
Cell type (subtype) | Mature erythrocytes |
Cell marker | Hba-a2, Gata1, Klf1, Epor, Gata2 |
Frequency | |
PubMed ID | 30890159 |
Journal | Genome Biology |
SCI IF | 10.806 |
Evidence | changes across all datasets—we observe changes of erythroid maturity marker genes (Gata2, Gata1, Klf1, Epor, and Hba-a2) along the erythroid trajectory through the PAGA graphs and observe sequential activation of these genes in agreement with known behavior. Acti-vation of neutrophil markers (Elane, Cepbe, and Gfi1) and monocyte markers (Irf8, Csf1r, and Ctsg) are seen towards the end of the neutrophil and monocyte trajectories, respectively |
Title | GAPA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells |
Authors | F. Alexander Wolf et al. |
Date | 2019 |
Data available | NA |