| ID |
4745 |
| Class |
Mammalia |
| Species |
Mouse |
| Tissue |
Blood |
| Sample |
Tissue |
| Disease type |
Normal |
| Cell type |
Emergency megakaryocytic stem-like population |
| Cell type (subtype) |
Emergency megakaryocytic stem-like population |
| Cell marker |
Itga2b, Pf4, Gata1, Isg15, Isg20, Stat1 |
| Frequency |
|
| PubMed ID |
31406379
|
| Journal |
Nat Immunol |
| SCI IF |
20.479 |
| Evidence |
The analysis of the specific gene expression patterns related to each cluster allowed us to determine that cells in cluster 4 expressed a gene signature previously described for an emergency megakaryocytic stem-like population32, 33, which included hematopoietic markers such as Itga2b (CD41), Pf4 and Gata1, together with IFN response genes such as Isg15 and Isg20 |
| Title |
The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation |
| Authors |
Maria Guillamot et al. |
| Date |
2019.9 |
| Data available |
GSE112542 |
