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ID 3899
Class Mammalia
Species Homo sapiens
Tissue Placentas
Sample Organoids
Disease type NA
Cell type The non-proliferative nature of npictbs
Cell type (subtype) The non-proliferative nature of npictbs
Cell marker XIST, DDX3X, EIF1AX, PAGE4
Frequency
PubMed ID 31829938
Journal eLife
SCI IF 7.08
Evidence The non-proliferative nature of npiCTBs was evidenced by the reduced expression of genes involved in cell proliferation such as XIST, DDX3X, and EIF1AX (Figure 1—figure supplement 3). npiCTBs displayed an increased expression of PAGE4 (Figure 1—figure supplement 3), a gene expressed by CTBs isolated from pregnancy terminations (Genbacev et al., 2011), suggesting that this type of trophoblast cell is present earlier in gestation
Title Single cell transcriptional signatures of the Human placenta in term and preterm parturition
Authors Roger Pique-Regi et al.
Date 2019.12
Data available GSE114037, GSE96083