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ID 4542
Class Mammalia
Species Homo sapiens
Tissue Thymus
Sample Tissue
Disease type thymus organogenesis
Cell type Progenitor cells
Cell type (subtype) Fetal ETP1
Cell marker CD34, SPINK2 , TRDC, RUNX3, IGLL2
Frequency
PubMed ID 31604687
Journal Immunity
SCI IF 31.745
Evidence Embryonic ETP and fetal ETP1 were characterized by the expression of stem and progenitor cells markers CD34 and SPINK2 (He et al., 2005), T cell receptor (TCR) gene TRDC (Dik et al., 2005; Joachims et al., 2006), T-lineage-related transcription factor (TF) gene RUNX3 (Tokunaga et al., 2009), and B-lymphoid lineage-related gene IGLL1 (Kuo et al., 2009), suggesting a multi-lineage potential
Title Single-Cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos
Authors Yang Zeng et al.
Date 2019.11
Data available GSE133341