Search | Result
| ID | 4541 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Thymus |
| Sample | Tissue |
| Disease type | thymus organogenesis |
| Cell type | Progenitor cells |
| Cell type (subtype) | Embryonic ETP |
| Cell marker | CD34, SPINK2 , TRDC, RUNX3, IGLL1 |
| Frequency | |
| PubMed ID | 31604687 |
| Journal | Immunity |
| SCI IF | 31.745 |
| Evidence | Embryonic ETP and fetal ETP1 were characterized by the expression of stem and progenitor cells markers CD34 and SPINK2 (He et al., 2005), T cell receptor (TCR) gene TRDC (Dik et al., 2005; Joachims et al., 2006), T-lineage-related transcription factor (TF) gene RUNX3 (Tokunaga et al., 2009), and B-lymphoid lineage-related gene IGLL1 (Kuo et al., 2008), suggesting a multi-lineage potential |
| Title | Single-Cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos |
| Authors | Yang Zeng et al. |
| Date | 2019.11 |
| Data available | GSE133341 |
