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ID 2743
Class Mammalia
Species Homo sapiens
Tissue Kidney
Sample Organoids
Disease type Autosomal recessive polycystic kidney disease
Cell type Endoderm cells
Cell type (subtype) Endoderm cells
Cell marker GATA6, AFP
Frequency
PubMed ID 31303547
Journal Cell Stem Cell
SCI IF 20.86
Evidence Gene expression profiling of pluripotency markers (OCT4, NANOG), mesoderm markers(ACTA2, MSX1), ectoderm markers (PAX6, FGF5), and endoderm markers (GATA6, AFP) in H9ESCs and isogenic ARPKD iPSCs (epi-17, cor-15, cor-24, cor-40), and embryonic bodies derivedfrom isogenic ARPKD iPSCs.
Title Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
Authors Jian Hui Low et al.
Date 2019.9
Data available GSE132026