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ID 2652
Class Mammalia
Species Homo sapiens
Tissue Kidney
Sample Organoids
Disease type Autosomal recessive polycystic kidney disease
Cell type Primitive streak
Cell type (subtype) Primitive streak
Cell marker T, MIXL1
Frequency
PubMed ID 31303547
Journal Cell Stem Cell
SCI IF 20.86
Evidence Immunofluorescence analysis for markers of primitive streak (T and MIXL1), nephrogenic intermediate mesoderm (WT1 and HOXD11), nephron progenitor (SALL1 and SIX2), pre-tubular aggregate (LHX1 and PAX8), podocyte (NPHS1), vascular progenitor (KDR), and Endothelial cellss (CD31) during differentiation
Title Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
Authors Jian Hui Low et al.
Date 2019.9
Data available GSE132026