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ID 2577
Class Mammalia
Species Homo sapiens
Tissue Islets
Sample Tissue
Disease type Many different diseases
Cell type Islet cells
Cell type (subtype) Islet beta cells
Cell marker INS, MAFA, PSCK1, ADCYAP1, PFKFB2, RBP1, SIX3
Frequency
PubMed ID 30760930
Journal Nature
SCI IF 49.962
Evidence 115 beta-related genes were upregulated in alphaPM, comprising important functional beta-cell markers like INS, MAFA (endogenous), PSCK1, ADCYAP1, PFKFB2, RBP1 and SIX3 (Fig. 3e, Supplementary Table 12).
Title Diabetes relief in Mouse by glucose-sensing insulin-secreting Human alpha-cells
Authors Kenichiro Furuyama et al.
Date 2019.3
Data available GSE118257