Search | Result
ID | 2364 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Heart |
Sample | Cell line |
Disease type | NA |
Cell type | Cardiac cells |
Cell type (subtype) | Cardiac progenitors |
Cell marker | ISL1, CKIT, MESP1, MESP2 |
Frequency | |
PubMed ID | 32619518 |
Journal | Cell Stem Cell |
SCI IF | 25.269 |
Evidence | Importantly, GSK-3beta inhibition did not result in increased expression of the cardiac progenitor markers such as CKIT, ISL1 or MESP1/2 (Figure S2F), suggesting that expansion of functional hiPSC-CMs with CHIR does not lead to expansion of a rare population of residual cardiac mesoderm or second-heart-field progenitor cells. |
Title | Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes |
Authors | Jan W Buikema et al. |
Date | 2020.7 |
Data available | GSE148586 |