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ID 2134
Class Mammalia
Species Homo sapiens
Tissue Embryonic stem cells
Sample Cell line
Disease type NA
Cell type Progenitor cells
Cell type (subtype) Ventral midbrain progenitors
Cell marker EN1, LMX1A, RSPO2, FOXA2
Frequency
PubMed ID 32451506
Journal Nat Biotechnol
SCI IF 36.558
Evidence These data showed that ventral forebrain progenitors (SIX3+, SIX6+ and NKX2-1+) were derived exclusively from regions A and B whereas ventral midbrain progenitors (EN1+, LMX1A+, RSPO2+ and FOXA2+) were derived mainly from region C and hindbrain cells (NKX6-2+, PHOXB2+, HOXB2+) mainly from regions D and E
Title Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
Authors Pedro Rifes et al.
Date 2020.11
Data available GSE135399