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ID 1668
Class Mammalia
Species Homo sapiens
Tissue Brain
Sample Organoids
Disease type NOD/scid/IL2rg (NSG)
Cell type Endothelial cells
Cell type (subtype) Endothelial cells
Cell marker CLDN5, PECAM1, CDH5, CD34, RGS5, ERG, PDGFRB, CD248
Frequency
PubMed ID 32961131
Journal Cell
SCI IF 38.653
Evidence Figure 5B. We also identified subsets expressing the endothelial and microglial markers CD248 and CSF1R, respectively. These populations were identified based on the expression canonical marker genes; mural cells specifically expressed expected marker genes, such as PDGFRB, FOXF2, RGS5, and CD248, while Endothelial cellss expressed a distinct set of markers, including CDH5 and PECAM1 (CD31; Figure 1D). Figure 1F
Title Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
Authors Kevin R Parker et al.
Date 2020.1
Data available GSE153647