Search | Result
| ID | 1666 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Brain |
| Sample | Organoids |
| Disease type | NOD/scid/IL2rg (NSG) |
| Cell type | B cells |
| Cell type (subtype) | B cells |
| Cell marker | CD79A, CD20, B220 |
| Frequency | |
| PubMed ID | 32961131 |
| Journal | Cell |
| SCI IF | 38.653 |
| Evidence | This revealed the presence of a CD45-high CD19+ B cell population, as expected, and also revealed a rare population of CD45-CD19+ cells, which expressed CD19 at a similar level to B cells but did not express the B cell marker B220 (Figures S5A_S5C). Figure 1F. Importantly, this population was negative for the B cell marker CD79A, arguing against the possibility of artifactual CD19 expression due to B cell-pericyte doublets (Figure 1E). |
| Title | Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies |
| Authors | Kevin R Parker et al. |
| Date | 2020.1 |
| Data available | GSE153647 |
