Search | Result
ID | 1308 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Blood |
Sample | NA |
Disease type | Stage IV metastatic melanoma |
Cell type | CD8 T cells |
Cell type (subtype) | CD8+CD39_CD69_ TIL |
Cell marker | LEF1, IL7R, SELL, TCF7, KLF2, CD27, S1PR1 |
Frequency | |
PubMed ID | 33303615 |
Journal | Science |
SCI IF | 41.845 |
Evidence | Cluster 1, which was four times more abundant in CR infusion products relative to NR infusion products (corrected P = 0.0264; Fig. 1D), corresponded to CD8+ T cells with high expression of CD44, CD27, and CD28 and low expression of TIM3, characterized in prior studies as memory-like (18) and stem-like (22) T cells (Fig. 1C) |
Title | Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against Human cancer |
Authors | Krishna et al. |
Date | 2020.12 |
Data available | NA |