Evidence |
This analysis generated four major cellular groups (Figures 1B and 1C), which were annotated_ posteriori_rom the expression of pre-selected signature transcripts, including the cell-fate determinant transcription factor Atoh1a (UHCPs and immature hair cells) [18, 19]; the Notch ligand DlD (UHCPs and immature hair cells) [20]; the molecular motor myo6b (immature and mature hair cells) [21, 22]; the cytosolic calcium buffers pvalb8, s100t, and s100s (mature hair cells) [23, 24]; as well as tekt3 [22, 25] and tmc2b [26] (mature hair cells), sost [7], klf17, stm, and si |