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ID 996
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Blood
Disease type COVID-19
Cell type Neutrophils
Cell type (subtype) Neutrophils
Cell marker G0S2, RSAD2, IL1R2, IL1RN
Frequency
PubMed ID 32810439
Journal Cell
SCI IF 38.637
Evidence we identified 5 regions based on DEGsacross pooled data from all samples (Figures 7F and S7I), including T cells (characterized by expression the NKG7, CD8A, CST7, GZMB, and GZMA genes), B cells (IGLV3-19, IGHV4-34, IGHG1, IGHA1, and JCHAIN), neutrophils (G0S2, RSAD2, IL1R2, and IL1RN), alveolar macrophages (APOE, MSR1, MARCO, and FBP1), and monocytes/macrophages(FN1, CXCL10, CD68, and NUPR1).
Title Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19
Authors Aymeric Silvin et al.
Date 2020.9
Data available GSE145926