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ID 9000
Class Mammalia
Species Mouse
Tissue Vasculature, skin
Sample Tissue
Disease type NA
Cell type T cells
Cell type (subtype) A short-lived effector Treg cell subset
Cell marker Foxp3, CD4, CD49b
Frequency
PubMed ID 30355617
Journal J Exp Med
SCI IF 11.743
Evidence We have identified a short-lived effector Treg cell subset that expresses the alpha2 integrin, CD49b, and exhibits a unique tissue distribution, being abundant in peripheral blood, vasculature, skin, and skin-draining lymph nodes, but uncommon in the intestines and in viscera-draining lymph nodes.
Title CD49b defines functionally mature Treg cells that survey skin and vascular tissues.
Authors Xiying Fan et al.
Date 2018.11
Data available GSE121034