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ID 6206
Class Mammalia
Species Mouse
Tissue Gastruloids
Sample Tissue
Disease type Normal
Cell type Ectoderm cells
Cell type (subtype) Primordial-germ-cell-like or extra-embryonic ectoderm
Cell marker Utf1, Ephx2, Mt1, Pou5f1
Frequency
PubMed ID 32076263
Journal Nature
SCI IF 49.962
Evidence Olfr129_nd_necut1, head mesenchyme (cluster9);_tv2, haemato-endothelial progenitors (bottom part of cluster10);_dr, haemato-endothelial progenitors and endothelium (cluster10);_dh5_nd_ie1, endothelium (top part of cluster10);_bx4, _oxa11, _ss1_nd_mp7, allantois (cluster11);_phx2, _t1, _tf1_nd_ou5f1, primordial-germ-cell-like or extra-embryonic ectoderm (cluster12);_ol4a1, _pcam_nd_ox17, endoderm (cluster13)._, Mean log normalized expression of relevant markers of clusters 1_8 plotted on the UMAP plot from Fig.1a._and2_nd_ata6, heart (cluster1);_eox2_nd_ax3, differentiated somite (cluster3);_ldh1a2_nd_ncx4.1, somite (cluster4);_fng, _esp2, _ipply2_nd_ll1, differentiation front (cluster5);_es7_nd_bx6, presomitic mesoderm (cluster 6);_nt3a, _gf17, _gf8, _yp26a1, _kx1-2_nd_, tail bud containing neuromesodermal progenitors (cluster7);_ax6, _ox1, _es3_nd_ox2, differentiated neural cells (spinal cord; cluster8).
Title Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids
Authors Susanne C. van den Brink et al.
Date 2020.2
Data available GSE123187