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ID 8718
Class Mammalia
Species Mouse
Tissue Spinal cord
Sample Tissue
Disease type Experimental autoimmune encephalomyelitis
Cell type T cells
Cell type (subtype) T helper cells
Cell marker Cd4, Cd3e, Cd3d, Cd3g
Frequency
PubMed ID 32149735
Journal J Clin Invest
SCI IF 12.282
Evidence Hierarchical clustering of the cells identified 5 main clusters of immune cells (Figure 3A), which expressed canonical markers of microglia (Tmem119, _2ry12, and_x3cr1), macrophages (Cd14, _yz2, _y6c2, and_d68), Th cells (Cd3d, _d3e, _d3g, and_d4), granulocytes (Retnlg, _100a8, and_100a9), and dendritic cells (Kmo, _lt3, _cr7, and_cl17) (Figure 3A)
Title Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS
Authors Zhilin Li et al.
Date 2020.4
Data available GSE129105