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ID 8681
Class Mammalia
Species Mouse
Tissue Small intestine
Sample Tissue
Disease type Normal
Cell type Amplifying cells
Cell type (subtype) Transit amplifying cells
Cell marker Lgr5, Gjb3, Fgfbp1
Frequency
PubMed ID 28467820
Journal Nature
SCI IF 49.962
Evidence Transit amplifying cells (cluster 2) were classified based on the enrichment of cell cycle markers and lack of Lgr5+ stem cell marker expression. Interestingly, there are genes that are specifically enriched in cluster 2, such as Gjb3 and Fgfbp1.
Title Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem cell self-renewal
Authors Kelley S. Yan, et al.
Date 2017.5
Data available GSE92865