| Evidence |
dividing cells (Mki67 and Top2a), while cluster 2 was distinguished by transcripts encoding molecules associated with effector CD8+ T cells (Cx3cr1, Klrc1 and Klrd1) (Supplementary Fig. 1b, c and Supplementary Table 1). A small cluster (cluster 3, 1.3% of total cells) expressed genes encoding markers of naive cells (Ccr7, Lef1 and Sell), probably representative of contaminating naive T cells. Several transcripts upregulated in cluster 4 (Tcf7 and Id3) were associated with a stem-like or progenitor population of exhausted CD8+ T cells in LCMV12_17 |
