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ID 8648
Class Mammalia
Species Mouse
Tissue Skin
Sample Cell line
Disease type NA
Cell type T cells
Cell type (subtype) Regulatory T cells (Treg)
Cell marker Foxp3
Frequency
PubMed ID 30552023
Journal Immunity
SCI IF 31.745
Evidence The cell clusters, visualized with t-stochastic neighbor embedding (t-SNE; Figures 2A and S2A) or force-directed graph layouts (SPRING) (Figure S2B; Weinreb et al., 2018), identified the following populations conventional T (Tconv) cells expressing Cd3e, regulatory T (Treg) cells expressing the transcription factor forkhead box P3 (Foxp3), natural killer (NK) cells expressing natural cytotoxicity triggering receptor 1(Ncr1) and killer cell lectin-like receptor subfamily B member 1c (Klrb1c), neutrophils (Neu) expressing C-X-C motif chemokine receptor 2 (Cxcr2) and G0/G1 switch 2 (G0s2), monocytes (Mo) and macrophages (Macs) expressing colony stimulating factor 1 receptor (Csf1r), and two DC subsets, referred to as DC1 and DC2
Title Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-g and IL-12
Authors Christopher S Garris et al.
Date 2018.12
Data available GSM3090155