ID |
6483 |
Class |
Mammalia |
Species |
Mouse |
Tissue |
Heart |
Sample |
Tissue |
Disease type |
athero-prone aortic arch (AA) and the more disease-resistant descending thoracic aorta (DT) |
Cell type |
Muscle cells |
Cell type (subtype) |
VSMC-lineage cells |
Cell marker |
Acta2, Myh11, Tagln, Ly6a |
Frequency |
|
PubMed ID |
30385745
|
Journal |
Nat Commun |
SCI IF |
12.121 |
Evidence |
Combining scRNA-seq with VSMC lineage tracing, we reveal a rare subset of VSMC-lineage cells expressing Stem Cell Antigen 1 (Sca1, encoded by Ly6a, referred to below as Ly6a/ Sca1). |
Title |
Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy Mouse vessels |
Authors |
Lina Dobnikar et al. |
Date |
2018.12 |
Data available |
GSE79436, GSE117963 |