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ID 6483
Class Mammalia
Species Mouse
Tissue Heart
Sample Tissue
Disease type athero-prone aortic arch (AA) and the more disease-resistant descending thoracic aorta (DT)
Cell type Muscle cells
Cell type (subtype) VSMC-lineage cells
Cell marker Acta2, Myh11, Tagln, Ly6a
Frequency
PubMed ID 30385745
Journal Nat Commun
SCI IF 12.121
Evidence Combining scRNA-seq with VSMC lineage tracing, we reveal a rare subset of VSMC-lineage cells expressing Stem Cell Antigen 1 (Sca1, encoded by Ly6a, referred to below as Ly6a/ Sca1).
Title Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy Mouse vessels
Authors Lina Dobnikar et al.
Date 2018.12
Data available GSE79436, GSE117963