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ID 8626
Class Mammalia
Species Mouse
Tissue Skin
Sample Cell line
Disease type NA
Cell type Neutrophils
Cell type (subtype) Neutrophils
Cell marker Cxcr2, G0s2
Frequency
PubMed ID 30552023
Journal Immunity
SCI IF 31.745
Evidence The cell clusters, visualized with t-stochastic neighbor embedding (t-SNE; Figures 2A and S2A) or force-directed graph layouts (SPRING) (Figure S2B; Weinreb et al., 2018), identified the following populations conventional T (Tconv) cells expressing Cd3e, regulatory T (Treg) cells expressing the transcription factor forkhead box P3 (Foxp3), natural killer (NK) cells expressing natural cytotoxicity triggering receptor 1(Ncr1) and killer cell lectin-like receptor subfamily B member 1c (Klrb1c), neutrophils (Neu) expressing C-X-C motif chemokine receptor 2 (Cxcr2) and G0/G1 switch 2 (G0s2), monocytes (Mo) and macrophages (Macs) expressing colony stimulating factor 1 receptor (Csf1r), and two DC subsets, referred to as DC1 and DC2
Title Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-g and IL-12
Authors Christopher S Garris et al.
Date 2018.12
Data available GSM3090155