Search | Result

ID 8614
Class Mammalia
Species Mouse
Tissue Skin
Sample Tissue
Disease type Melanoma
Cell type Macrophages
Cell type (subtype) Pro-tumorigenic M2 state
Cell marker Itgam, Arg1, Chil3, Adgre2, TGFb1
Frequency
PubMed ID 30721153
Journal JCI Insight
SCI IF 6.205
Evidence CD11b+F4/80+ macrophages in tumors grown in miR-155 TCKO Mouse expressed higher levels of Arginase 1 (Arg1), tumor growth factor-beta (TGFb1) and chitinase-like 3 (Chil3, also known as Ym1), which are commonly used markers to define pro-tumorigenic M2 state
Title MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in Human cancers.
Authors H. Atakan Ekiz et al.
Date 2019.3
Data available GSE121478