Evidence |
The cell clusters, visualized with t-stochastic neighbor embedding (t-SNE; Figures 2A and S2A) or force-directed graph layouts (SPRING) (Figure S2B; Weinreb et al., 2018), identified the following populations conventional T (Tconv) cells expressing Cd3e, regulatory T (Treg) cells expressing the transcription factor forkhead box P3 (Foxp3), natural killer (NK) cells expressing natural cytotoxicity triggering receptor 1(Ncr1) and killer cell lectin-like receptor subfamily B member 1c (Klrb1c), neutrophils (Neu) expressing C-X-C motif chemokine receptor 2 (Cxcr2) and G0/G1 switch 2 (G0s2), monocytes (Mo) and macrophages (Macs) expressing colony stimulating factor 1 receptor (Csf1r), and two DC subsets, referred to as DC1 and DC2 |