Search | Result

ID 7245
Class Mammalia
Species Mouse
Tissue Liver
Sample Tissue
Disease type Normal
Cell type Hepatocytes
Cell type (subtype) Periportal PP hepatocytes
Cell marker Alb, Ttr, Apoa1, Serpina1c, Pck1, Cyp2f2, Hal, Cdh1
Frequency
PubMed ID 30283141
Journal Nature
SCI IF 49.962
Evidence Hepatocyte-specific genes are broadly expressed, including Alb, Ttr, Apoa1, and Serpina1c. Using known zonated metabolic genes, we could identify within this population PC hepatocytes (Cyp2e1+ , Glul+ , Oat+ , Gulo+ ), periportal PP hepatocytes (Cyp2f2+ , Pck1+ , Hal+ , Cdh1+ ), and midlobular (ML) hepatocytes (Cyp2e1low or Cyp2f2low , Ass1high , Hamphigh , Gstp2high , Ubbhigh)
Title Single-cell transcriptomics of 20 Mouse organs creates a Tabula Muris
Authors Nicholas Schaum et al.
Date 2018.1
Data available GSE109774