| ID |
1541 |
| Class |
Mammalia |
| Species |
Homo sapiens |
| Tissue |
Brain |
| Sample |
Organoids |
| Disease type |
Multiple sclerosis |
| Cell type |
T cells |
| Cell type (subtype) |
Memory T cells |
| Cell marker |
S100A4 |
| Frequency |
|
| PubMed ID |
32948672
|
| Journal |
Sci Immunol |
| SCI IF |
13.423 |
| Evidence |
Two clusters predominantly present in the blood were na_ve CD4 (CD4 na_ve blood) and na_ve CD8 (CD8 na_ve blood) that were defined by expression of genes including CCR7, SELL, and LEF1. The blood also contained a cluster of CD4 T cells (CD4 memory blood) marked by expression of molecules associated with memory T cells (S100A4) and markers of various T cell subsets including the TH2 transcription factor GATA3 and the TH17 marker KLRB1 (CD161) |
| Title |
Transcriptomic and clonal characterization of T cells in the Human central nervous system |
| Authors |
Jenna L Pappalardo et al. |
| Date |
2020.9 |
| Data available |
phs002222.v1.p1, GSE157277, GSE155488 |
