Evidence |
we identified 10 distinct populations. This includes many previously characterized pancreatic cell types based on known cell-specific transcripts beta (Ins1+ , Ins2+ , Slc2a2+ , Nkx6- 1+ , Pdx1+ , and Mafa+ ), alpha (Gcg+ , Mafb+ , and Arx+ ), delta (Sst+ , Hhex+ , and Pdx1+ ), and PP cells (Ppy+ , Mafbneg, and Spp1+ ) of islets, as well as acinar (Amy2b+ , Cpa1+ , and Ptf1a+ ), ductal (Krt19+ and Hnf1b+ ), endothelial (Pecam1+ , Cdh5+ , and Kdr+ ), immune (Ptprc+ ), and pancreatic stellate cells (Pdgfra+ and Pdgfrb+ ) |