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ID 7994
Class Mammalia
Species Mouse
Tissue Ovary
Sample Tissue
Disease type Normal
Cell type Granulosa cells
Cell type (subtype) Pre-granulosa cells
Cell marker Wnt4, Wnt6, Kitl, Foxl2
Frequency
PubMed ID 32759216
Journal Proc Natl Acad Sci U S A
SCI IF 9.351
Evidence These were germ cells (cluster 0 to 3) with Ddx4 and Dazl expression (46), epithelial cells (clusters 4 to 6) with Upk3b and Krt19 expression (47, 48), PG cells (clusters 7 to 13) with Wnt4, Wnt6, Kitl, and Foxl2 expression (49_51), mesenchymal cells (clusters 14 to 21) with Nr2f2 and Col1a1 expression (23, 52), and endothelial/blood-related cells (clusters 22 to 30) with Cldn5, Car2, Lcn2, and Cx3cr1 expression
Title Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary
Authors Wanbao Niu et al.
Date 2020.8
Data available GSE136441